2021 Toyota Sienna
The 2021 Toyota Sienna is a minivan, rated at 36 MPG combined by the EPA. NHTSA lists 2 recalls for this model year.
- Combined MPG
- 36
- NHTSA safety
- Not rated
- Starting price
- $38,000
- Recalls
- 2
Watch: Sienna reviews
Full specifications
Identity
SRC · NHTSA vPIC| Make | Toyota |
|---|---|
| Model | Sienna |
| Model year | 2021 |
| Vehicle class | Minivan |
Engine & drivetrain
SRC · EPA FuelEconomy| Displacement | 2.5 L |
|---|---|
| Cylinders | 4 |
| Transmission | Automatic (AV-S6) |
| Drivetrain | Front-Wheel Drive |
| Fuel | Regular Gasoline |
Fuel economy
SRC · EPA FuelEconomy| City MPG | 36 |
|---|---|
| Highway MPG | 36 |
| Combined MPG | 36 |
| CO₂ tailpipe | 246 g/mi |
| EPA annual fuel cost | $1750 |
Available configurations
SRC · EPA FuelEconomy| Sienna Hybrid 2WD | 36 MPG combined |
|---|---|
| Sienna Hybrid AWD | 35 MPG combined |
Fuel economy
SRC · EPA FuelEconomy| City | 36 MPG |
|---|---|
| Highway | 36 MPG |
| Combined | 36 MPG |
Efficiency vs class average
About 57% more efficient than the Sienna's class average.
- Amount financed
- $34,200
- Total interest
- $5,950
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≈ $1,117/yr · 12,000 mi/yr · $3.35/gal
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Cost to own
Estimate monthly payments and 5-year fuel cost using the tools in the sidebar. Figures use EPA fuel economy and current U.S. energy prices from EIA.
Safety ratings & recalls
SRC · NHTSA vPICNHTSA has not published NCAP crash-test ratings for this model year yet.
Recalls (2)
- ELECTRONIC STABILITY CONTROL (ESC):CONTROL MODULE:SOFTWARE22V239000 · 2022-04-13
Toyota Engineering & Manufacturing (Toyota) is recalling certain 2022 Lexus LX 600, Lexus NX 350h, Lexus NX 450h+, Toytoa RAV4 Hybrid, 2021-2022 Lexus LS 500h, Toyota Mirai, RAV4 PRIME, Sienna, Venza, and 2020-2022 Toyota Highlander Hybrid vehicles. The Skid Control ECU software may not turn on the Vehicle Stability Control (VSC) system when the vehicle is restarted after the driver has disabled the VSC system. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 126, "Electronic Stability Control Systems."
Remedy: Dealers will update the Skid Control ECU software, free of charge. Owner notification letters were mailed May 27, 2022. Owners may contact Toyota customer service at 1-800-331-4331. Toyota's number for this recall is 22TA03. Lexus' number for this recall is 22LA01.
- EQUIPMENT ADAPTIVE/MOBILITY:WHEELCHAIR RESTRAINTS/SECUREMENT:LATCH/ANCHOR:25V877000 · 2025-12-17
Vantage Mobility, LLC (VM) is recalling certain 2021-2026 Honda Odyssey, 2021-2025 Chrysler Pacifica, and Toyota Sienna vehicles equipped with QRT-Deluxe and QRT-Max wheelchair restraints. The retractors may not lock, preventing the wheelchair from being properly secured.
Remedy: Dealers will inspect and replace the retractors, free of charge. Owner notification letters was mailed January 27, 2026. Owners may contact Vantage Mobility customer service at 1-800-488-9082.
Compare with rivals
All model years
Frequently asked questions
What is the MPG of the 2021 Toyota Sienna?
The 2021 Toyota Sienna is EPA-rated at 36 MPG combined (36 city / 36 highway).
Is the 2021 Toyota Sienna reliable?
NHTSA lists 2 recalls for the 2021 Toyota Sienna. Recalls are repaired free of charge by the manufacturer — verify any open recalls by VIN before purchase.
How much does it cost to fuel the 2021 Toyota Sienna?
At 12,000 miles per year, the 2021 Toyota Sienna costs roughly $1,117 per year to fuel, or about $5,583 over 5 years at current U.S. energy prices.
What type of vehicle is the 2021 Toyota Sienna?
The 2021 Toyota Sienna is classified as a minivan. Common rivals in this class are worth comparing on price, MPG, and safety.
Sources: NHTSA vPIC · EPA FuelEconomy · NHTSA vPIC